Electronic Patient Reported Outcomes
Mobile-first questionnaire delivery with adaptive instruments, compliance monitoring, and real-time symptom tracking.
The Patient Voice, Captured Accurately
Maximize compliance rates and data quality with patient friendly outcome collection.
Validated Instrument Library
Pre configured library of 200+ validated PRO instruments including EQ-5D, PROMIS, SF-36, and disease-specific scales. Licensed, version controlled, and ready to deploy.
Adaptive Questionnaires
Conditional branching and computer-adaptive testing reduce respondent burden. Skip irrelevant questions automatically based on previous answers and clinical context.
Mobile First Delivery
Native iOS and Android apps with offline support, push notification reminders, and accessibility features. Patients complete assessments on their own devices, on their own schedule.
Compliance Monitoring
Real-time compliance dashboards track completion rates, response windows, and missing data patterns. Automated reminders and escalation workflows keep compliance above target.
Symptom & Safety Alerts
Configurable alert thresholds trigger real-time notifications to investigators when patient responses indicate safety concerns or clinically significant symptom changes.
Multi Modal Collection
Support for diary entries, visual analog scales, voice recordings, and photo capture. Collect the right type of data in the most natural format for each assessment.
Regulatory Ready Exports
Timestamped, audit trailed data with CDISC QRS compliance. Generate FDA and EMA-ready PRO analysis datasets with automated scoring and domain mapping.
AI-assisted questionnaire design
Early access Q2 2026Describe the questionnaire you need in plain language. Our AI-assisted builder generates the electronic CRF structure, validation rules, and skip logic. In active development, early access Q2 2026 for design partners.
Adaptive, AI-driven questionnaires that adjust in real time based on patient response patterns are in active development on the same Q2 2026 early-access track.
How It Works
From instrument selection to outcome analysis in three steps.
Configure Instruments
Select validated instruments from the library or build custom questionnaires. Define schedules, reminder cadences, and compliance windows for each assessment.
Collect Outcomes
Patients receive push notifications and complete assessments on their mobile devices. Real-time dashboards show compliance rates and flag patients who need follow-up.
Analyze & Report
Automated scoring, longitudinal trend analysis, and CDISC compliant dataset generation. Export regulatory ready PRO summaries for your clinical study report.
See it in action
Vitruvian Shield Questionnaire
Ready to Modernize Your Clinical Trials?
Join leading sponsors, CROs, and research sites using Vitruvian Shield to run faster, smarter, and more compliant trials.
Or contact our team for a personalized walkthrough.